Herbert T Nagasawa PhD on Glutathione (GSH) (AlcoholGSH)
- Enhancement of systemic immune function
The immune system works best if the lymphoid cells have properly balanced glutathione. The cloning of T-cells consumes large quantities of cysteine. Macrophages (type of white blood cells), which are only present in enough quintiles when there is enough glutathione, provide the cysteine for the T-cell cloning. Glutathione regulates the binding, internalization, degradation and T-cell proliferation by increasing, as much as two times, the number of binding cellular receptors. More receptors equate to more T-cells being produced simultaneously (multiple T-cell cloning). Cellular GSH also affects the growth and replication of T-cells through growth stimulating cytokines. http://www.immunehealthscience.com/glutathione.html
- Enhancement of humoral immune function
The role of glutathione in the humoral response is that it protects the cells taking part in the humoral response all along this complex process.
A quick synapsis of the humoral immune response: “humoral” means circulating in the bloodstream. This is an immune response (chiefly against bacterial invasion) that is mediated by B cells and involves the transformation of B cells into plasma cells that produce and secrete antibodies to a specific antigen.
The process in a nutshell: macrophages engulf and digest the invading pathogen. The digested pieces activate helper T cells which in turn activate the proliferation of B cells that are programed for the specific invading pathogen. http://www.immunehealthscience.com/glutathione.html